Christopher Z. Mabini, DO · MSAEd
Board-eligible Minimally Invasive Gynecologic Surgeon, Award-Winning Researcher, Educator, and AI/LLM Developer advancing the future of healthcare.
Combining surgical excellence, educational leadership, and cutting-edge artificial intelligence to redefine modern healthcare.
Dr. Christopher Mabini is a board-eligible minimally invasive gynecologic surgeon completing his Complex Benign Gynecology Fellowship at PRIME St. Francis Hospital in Evanston, IL. Trained as a Doctor of Osteopathic Medicine with an additional Anatomy & Osteopathic Principles fellowship, his practice integrates whole-person care with cutting-edge surgical and digital tools.
With a Master's in Adult Education specialized in curriculum development and a passion for technology, Dr. Mabini bridges traditional osteopathic philosophy with modern surgical practice and emerging AI capabilities — creating tools and care models that enhance both patient outcomes and surgical training.
Surgical Innovation: Indocyanine Green (ICG) imaging, Narrow-Band Imaging (NBI), advanced hysteroscopy, robotic myomectomy, and complex laparoscopy.
Research Leadership: Multiple IRB-approved studies on endometriosis detection, adenomyosis imaging, isthmocele repair, and ERAS protocols.
AI & Technology: Building LLM-powered applications for surgical education, patient engagement, and clinical decision support — with medical 3D printing and video production as complementary skills.
Education: Designed FMIGS institutional curriculum integrating AI and advanced technologies; mentored residents as Surgical Skills Chief.
A foundation built on osteopathic principles — where structure, function, and the body's innate capacity to heal inform every facet of women's health care.
Trained as a Doctor of Osteopathic Medicine (DO) with a competitive Anatomy & Osteopathic Principles and Practice Fellowship at ACOM, Dr. Mabini brings a uniquely integrative perspective to gynecologic surgery — one that views the patient as more than a single organ system.
Osteopathic Manipulative Medicine (OMM) and Osteopathic Manipulative Treatment (OMT) provide hands-on tools that complement surgical and medical management — addressing the musculoskeletal, fascial, and visceral connections that classical medicine often overlooks. In women's health, this means pelvic pain, dysmenorrhea, pregnancy-related discomfort, and post-surgical recovery can be approached not just with prescriptions or procedures, but with a deeper understanding of how the body's structures interact.
The osteopathic tenet — body, mind, and spirit work as a unit, with structure and function inseparably linked — shapes every consultation. Each patient is more than her symptoms.
Manual therapy techniques for pelvic floor dysfunction, dysmenorrhea, sacral imbalance, post-cesarean adhesion patterns, pregnancy-related musculoskeletal pain, and post-operative recovery.
An anatomy-fellowship-trained surgeon understands how scar, fascia, and visceral mobility shape outcomes — informing surgical planning and post-operative rehabilitation alike.
Continued training in the Fascial Distortion Model (FDM), Osteopathic Cranial techniques, and the SAAO Convocation — bringing nuanced manual approaches into modern OBGYN practice.
"The DO philosophy isn't an alternative to surgery — it's the lens that makes surgical care truly holistic. The best outcomes happen when we understand why the body presents the way it does, not just how to fix the immediate problem."
Hands-on AI/LLM development, applied to real clinical workflows. From patient education to surgical training, technology is the bridge to better outcomes.
Designing and deploying large language model applications for clinical decision support, surgical reference, and patient communication.
Embedding AI tools into MIGS workflows — from pre-op planning to post-op follow-up — designed and tested by an active surgeon.
FMIGS curriculum integrating AI/advanced tech, training the next generation of surgeons to leverage modern tools confidently.
Patient-specific anatomical models and surgical planning tools, bridging digital innovation with tangible clinical impact.
Award-winning surgical video editing — including the AAGL Golden Hysteroscope-winning video — combining clinical precision with cinematic storytelling.
Using AI to accelerate literature review, data analysis, and IRB documentation across multiple active studies.
Five purpose-built macOS applications powering clinical practice, board prep, research, and surgical education — engineered end-to-end with modern AI.
The flagship clinical companion — an AI assistant for the working OBGYN/MIGS surgeon, integrating evidence-based guidance with day-to-day clinical decision support.
Purpose-built for board-eligible OBGYNs — track, organize, and prepare your ABOG case list with the structure required for the oral exam.
AI-powered medical dictation and transcription — capture clinic notes, op notes, and patient encounters with speed and clinical accuracy.
An end-to-end research companion — managing active IRB studies, accelerating literature review, and supporting abstract and manuscript preparation.
The same video workflow that produced AAGL award-winning content — a dedicated archive and review tool for organizing, tagging, and learning from surgical footage.
Click any publication to reveal an AI-generated snapshot summary. Active IRB studies, multi-journal publications, and award-winning presentations.
Recipient of the AAGL Golden Hysteroscope Award for Best Video Abstract in Hysteroscopy at the AAGL Global Congress, New Orleans, 2024.
This award-winning case study demonstrates a precision hysteroscopic technique for removing retained products of conception (RPOC) from an angular pregnancy site within an arcuate uterus — anatomy that classically defies blind dilation and curettage. By using direct visualization, the team avoided traumatic blind instrumentation, preserved endometrial integrity, and maximized fertility-sparing potential. The video set a new teaching standard, recognized by AAGL with the Golden Hysteroscope Award.
DOI: 10.1007/s00404-025-08071-x
A 43-year-old patient with severe abnormal uterine bleeding and chronic pelvic pain after endometrial ablation presented a diagnostic puzzle: a uterine isthmocele complicated by altered tissue architecture. The team used Indocyanine Green (ICG) fluorescence imaging to precisely localize the defect and guide minimally invasive repair. The case — paired with a comprehensive literature review — illustrates how ICG enhances surgical precision, shortens operative time, and reduces complications, marking a meaningful advancement in isthmocele care.
DOI: 10.1016/j.jmig.2024.12.011
Using CT imaging from 194 patients stratified by WHO BMI categories, this study reveals that the deep epigastric vessels shift laterally with rising BMI — meaning classic "safe zone" landmarks for laparoscopic port placement become unreliable in obese patients. The recommendation: position trocars more than 10 cm from the midline when BMI exceeds 35. The findings directly impact surgical safety in a growing patient population, redefining a foundational laparoscopic teaching point.
Recipient of the George M. Morley Award for Best Gynecological Research at CAOG 2023.
Endometriosis-related fibrosis can be visually subtle, easily missed under standard white-light visualization. This award-winning research applies ICG fluorescence — typically used for vascular mapping — to highlight inflammatory and fibrotic tissue changes intraoperatively. The result is a more sensitive, real-time identification of disease, with implications for more complete excision and improved long-term symptom relief. The work earned the George M. Morley Award for Best Gynecological Research at CAOG 2023.
Presented at AAGL Global Congress, 2025 · IRB: RIL20240017
Adenomyosis remains a clinical chameleon — easy to suspect, harder to confirm. This retrospective cohort study evaluates Narrow Band Imaging (NBI) hysteroscopy as a real-time, in-office diagnostic enhancement. By emphasizing surface vascular patterns invisible to standard white light, NBI helps distinguish adenomyotic features (irregular endometrial surface, hypervascularization, strawberry pattern) from healthy tissue. The work supports a future where adenomyosis diagnosis is faster, less invasive, and more accurate.
Presented at AAGL Global Congress, New Orleans, 2024
Robotic myomectomy frequently bottlenecks at fibroid extraction. This work presents a streamlined "à la carte" technique using a gel-based port and bag containment system — reducing total operative time, simplifying multi-fibroid removal, and maintaining contained morcellation safety. A practical workflow innovation that translates directly to OR efficiency and patient outcomes.
Presented at AAGL Global Congress, New Orleans, 2024
Asherman's syndrome distorts uterine anatomy, complicating the already-difficult repair of an isthmocele. This case integrates ICG fluorescence into a combined hysteroscopic-robotic approach — using fluorescent guidance to identify the defect's true margins despite scarred terrain. The result: a precise, fertility-sparing repair that wouldn't be achievable through traditional means alone.
Active randomized controlled trial
An ongoing RCT investigating whether transversus abdominis plane (TAP) blocks meaningfully reduce post-operative pain in minimally invasive gynecologic surgery within an Enhanced Recovery After Surgery (ERAS) protocol. The study aims to add high-quality evidence to a pain management modality often used but unevenly studied in MIGS — directly informing future ERAS guidelines.
An infertility workup uncovered an unusually complex multifocal endometriosis — with atypical papillary fragments involving both the appendix and fallopian tube. This accepted manuscript documents the diagnostic pathway, surgical findings, and pathology, expanding the clinical understanding of how aggressively endometriosis can manifest beyond classical pelvic sites. Particularly relevant for fertility-focused MIGS workups.
National recognition for surgical excellence, research innovation, and educational leadership.
Best Video Abstract in Hysteroscopy, AAGL Global Congress, New Orleans
Best Gynecological Research, CAOG Annual Meeting, Indianapolis
American Association of Gynecologic Laparoscopists, PGY4 recognition
Ascension Illinois St. Alexius OBGYN Residency, PGY4 leadership
Ascension Illinois St. Alexius OBGYN Residency, PGY1
Chiari Malformations in Pregnancy — Ascension OBGYN Didactics
PRIME Illinois St. Francis Hospital, Evanston, IL — formerly Minimally Invasive Gynecologic Surgery (MIGS)
Ascension Illinois St. Alexius OBGYN Residency, Hoffman Estates, IL · ACGME 2201621094
Alabama College of Osteopathic Medicine, Dothan, AL
Concentration in Curriculum Development & Instructional Design · Troy University, Montgomery, AL
Alabama College of Osteopathic Medicine, Dothan, AL — competitive fellowship in human anatomy instruction and osteopathic manipulative medicine
University of Liverpool, U.K.
University of California, Irvine
Open to research collaborations, AI consulting, locum opportunities, and speaking engagements. Reach out for surgical excellence, educational design, or AI-powered healthcare innovation.